Program Opportunity Discovery Preclinical Phase I Phase II Upcoming Milestones
PHP-303
5th Generation Neutrophil Elastase Inhibitor 		AATD
Alpha-1 Antitrypsin Deficiency
  • Phase II (EU) Initiation
  • Phase II (EU) Data
  • Phase IIb (EU/US) Initiation
ARDS
Acute Respiratory Distress Syndrome
  • IND Submission
  • Phase II Initiation
TORPEDO™
Novel ADC Platform 		M2.9 PH1 ADC
Novel ADC targeting RNA splicing of Trop2-expressing solid tumors
  • IND Submission
  • Phase II Initiation
M5 PH1 ADC
Novel ADC targeting RNA splicing of an unnamed target expressed in solid tumors
  • Additional research collaborations
PH-5 & PH-6
Novel Toxin Research
  • Toxin PH5 and PH6 Go/No Go Decisions